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The FCS in international research on Clostridium difficile infection

Posted by miguel lamb

Our Faculty of Health Sciences has participated in an international investigation on the association of infection by Clostridium difficile with cognitive and functional impairment, and its impact on mortality in hospitalized elderly patients. The work, published in Journal of General Internal Medicine, It was carried out by professor María José Fernández Cotarelo together with doctors Jiménez Díez-Canseco and Sánchez Redondo from the Internal Medicine Service and doctor Pérez Pomata from the Microbiology Service of the University Hospital of Móstoles, in collaboration with researchers S. Nagy-Agren and B. Shenal of Salem Veterans Affairs Medical Center, C. Warren and M. Smolkin of the University of Virginia.

Photography: Julia Benito Rodriguez

 

The study, which can be read at: https://rdcu.be/brU3R, showed that infected patients present delirium more frequently during admission, deteriorate functionally and have higher overall mortality even in the months after discharge than other hospitalized patients of similar age and comorbidities. These results provide valuable clinical information on this infection, whose effects could go beyond the diseased intestine. Biomedical research thus continues to advance our understanding of the role of the gut-brain axis and the gut microbiota in various diseases. This international collaboration is the result of a stay in the United States financed by the Carlos III Health Institute, the Spanish Society of Internal Medicine (SEMI) and the Madrid-Castilla la Mancha Society of Internal Medicine (SOMIMACA).

Last modified on Wednesday, April 03, 2019 at 10:18 p.m.