This research, published in british journal of pharmacology, provides evidence about the link between the immune system and the vascular damage produced in arterial hypertension, a hypothesis that is being investigated by many groups worldwide.
The authors of the study have identified Kv1.3 potassium channels as new mediators involved in the worsening of vasodilator responses associated with arterial hypertension.
Participating in the research are the professors of the Department of Basic Health Sciences, Raquel Hernanz Martín and Marta Martínez Casales, members of the Consolidated Cardiovascular Research Group of the Rey Juan Carlos University
More info here: The role of Kv1.3 potassium channels in vascular damage produced in arterial hypertension has been identified | mothersd
Bibliographic reference:
Olivencia, MA, Martínez-Casales, M., Peraza, DA, García-Redondo, AB, Mondéjar-Parreño, G., Hernanz, R., Salaices, M., Cogolludo, A., Pennington, MW, Valenzuela, C ., Briones, AM 2021. KV1.3 channels are novel determinants of macrophage-dependent endothelial dysfunction in a mouse model with angiotensin II-induced hypertension. British Journal of Pharmacology, DOI: 10.1111/bph.15407