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FCS research tips: Kv1.3 potassium channels and vascular damage in high blood pressure

Posted by FMR

The study is a collaboration between groups from the UAM, the CSIC, the UCM and the URJC

This research, published in british journal of pharmacology, provides evidence about the link between the immune system and the vascular damage produced in arterial hypertension, a hypothesis that is being investigated by many groups worldwide.

The authors of the study have identified Kv1.3 potassium channels as new mediators involved in the worsening of vasodilator responses associated with arterial hypertension.

Participating in the research are the professors of the Department of Basic Health Sciences, Raquel Hernanz Martín and Marta Martínez Casales, members of the Consolidated Cardiovascular Research Group of the Rey Juan Carlos University

More info here: The role of Kv1.3 potassium channels in vascular damage produced in arterial hypertension has been identified | mothersd

Bibliographic reference:

Olivencia, MA, Martínez-Casales, M., Peraza, DA, García-Redondo, AB, Mondéjar-Parreño, G., Hernanz, R., Salaices, M., Cogolludo, A., Pennington, MW, Valenzuela, C ., Briones, AM 2021. KV1.3 channels are novel determinants of macrophage-dependent endothelial dysfunction in a mouse model with angiotensin II-induced hypertension. British Journal of Pharmacology, DOI: 10.1111/bph.15407

Last modified on Thursday, February 25, 2021 at 15:31