Responsible: Gemma Medina Gomez Address: Department of Basic Health Sciences. Health Sciences Faculty. Avda de Atenas s/n. 28922 Alcorcon. Department: Department of Basic Health Sciences Phone: 91 488 86 32. |
Description of the service/Trials offered
Our vision is to create a space for in vivo, ex vivo murine phenotyping and molecular phenotyping that would be integrated into the characterization of metabolic diseases in murine models. In short, this laboratory is proposed as a service to the scientific community.
The specific objectives of the metabolic phenotyping laboratory for experimental animals are:
- advance science and enable the development of economically competitive research programs by providing metabolic phenotyping using a variety of standardized protocols
- develop a core of facilities that can become self-sufficient through a cost-recovery business model that could primarily serve academics but would also be open to businesses.
- attract more well-funded research programs by providing them with state-of-the-art services at a realistic competitive cost.
- train researchers in standardized approaches to the study of murine metabolism as next-generation experts capable of interpreting animal disease from a multidisciplinary perspective.
The laboratory has basic specialized facilities to provide state-of-the-art murine metabolic phenotyping; support for industrial/pharma/biotechnology and academic users as a single, centralized resource within the Community of Madrid, as well as for any hospital and/or scientific group or pharmaceutical industry in the area, to develop and apply new techniques to assess metabolic alterations and behavior in animal models, genetically modified or subjected to various pharmacological treatments.
El LAFEMEX incorporates the technology of a Comprehensive Laboratory Animal Monitoring System or CLAMS for food intake, food preferences, body weight, energy expenditure and indirect calorimetry, as well as activity studies, study of biochemical parameters and study of carbohydrate metabolism with glucose and insulin tolerance test measures. This technology is essential given the need to provide tools and resources to the scientific community for phenotyping not only of transgenic models, but also to be able to carry out studies on trials of any type of drug and its repercussions on the parameters described above.